Dr. Myron N.V. Williams

Associate Professor

Department of Chemistry

Clark Atlanta University

mnwill@cau.edu

Office: 404-880-6856

Fax: 404-880-6898

Research Interest

Identification and measurement of biomarkers of human disease, particularly prostate cancer.
Design, selection and production of recombinant proteins through phage display and microbial biotechnologies.
Development and application of low cost and appropriate molecular technologies.

Education

BS, 1980, Howard University, Microbiology

PhD, 1989, Massachusetts Institute of Technology, Biology

Publications

Signer ER, Sharma SB, Williams MNV, Bent A, Clover R, Wacks D, Kieber J and Klein S. 1988. Search for new symbiotic genes in Rhizobium meliloti. In: Molecular Genetics of Plant-Microbe Interactions 1988 (R. Palacios and D.P.S. Verma, Eds.) APS Press, St. Paul, MN.

Williams MNV, Klein S and Signer ER. 1989. Host restriction and transduction in Rhizobium meliloti. Appl. Env. Microbiol. 55:3229-3230.

Williams MN, Hollingsworth RI, Klein S and Signer ER. 1990. The symbiotic defect of Rhizobium meliloti exopolysaccharide deficient mutants is suppressed by lpsZ, a gene involved in lipopolysaccharide synthesis. J. Bacteriol. 172:2622-2632.

Williams MNV and Signer ER. 1990. Metabolism of tryptophan and tryptophan analogs by Rhizobium meliloti. Plant Physiol. 92:1009-1013.

Williams MN, Hollingsworth RI, Brzoska PM, and Signer ER. 1990. Chromosomal loci of Rhizobium meliloti required for suppression of exopolysaccharide mutations by lipopolysaccharide. J. Bacteriol. 172:6596-6598.

Williams,MNV, Pande NT, Nair S, Mohan M, and Bennett J. 1991. Restriction fragment length polymorphism analysis of mapped loci amplified by polymerase chain reaction from rice (Oryza sativa) genomic DNA. Theor. Appl. Genet. 82:489-4987.

Bennett J,Williams MNV, Mohan M, and Nair S. 1993. Molecular Approaches to the Enhancement of Insect Resistance in Rice. In: New Frontiers in Rice Research (K. Muralidharan and E.A. Siddiq, Eds) Directorate of Rice Research, Hyderabad. p. 172-176.

Albersheim P, An J, Freshour G, Fuller MS, Guillén R, Ham K-S, Hahn MG, Huang J, O'Neill M, Whitcombe A, Williams MV, York WS, & Darvill A. 1994. Structure and function studies of plant cell wall polysaccharides. Biochem Soc Trans, 22:374-378.

Reuhs BL, Williams MNV, Kim JS, Carlson RW and Côté, F. 1995. Suppression of the Fix- phenotype of Rhizobium meliloti exoB mutants by lpsZ is correlated to a modified expression of the K polysaccharide. J. Bacteriol. 177:4289-4296.

Williams MNV, Freshour G, Darvill AG, Albersheim P, and Hahn MG. 1996. An antibody Fab selected from a recombinant phage display library detects deesterified pectic polysaccharide rhamnogalacturonan II in plant cells. The Plant Cell 8:673-685.

Johnson KP, Rowe G, Jackson BA, D'Agostino J, Campbell PE, Guillory BO, Charles GM, Veret CR, DeLeon M. Williams, MNV, Matthews QL, and Johnson DE, and Cooke DB. 2001. Novel antineoplastic isochalcones inhibit the expression of cyclooxygenase 1,2 and EGF in human prostate cancer cell line LNCaP Cellular and Molecular Biol., 47(6):1039-1046.

Chiang CF, Okou DT, Griffin TB, Verret CR, and Williams MNV. 2001. Green Fluorescent Protein Rendered Susceptible to Proteolysis: Positions for Protease Sensitive Insertions. Archiv Biochem. Biophys. 394, 229-235.

Okou DT, Chiang CF, Griffin TB, Verret CR, and Williams MNV. A Bifunctional Fusion Protein Comprising GFP and a Single Chain Fv. Submitted

Okou DT, Kimbro KS, Haider J, Moore J.‐A., and Williams MNV. Expression profiling of Ki‐Ras transformed human prostatic cell lines. Submitted